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<p>Dilated cardiomyopathy is the leading reason for heart transplantation in children. Tachycardia-induced cardiomyopathy (TIC), or tachycardiomyopathy (TCM), is a&#xa0;reversible subgroup of cardiomyopathy; therefore, it is important to differentiate this form from other etiologies. Both the electrophysiological substrate of TCM and the clinical picture can be very diverse as shown based on four case examples. The most frequent arrhythmias that can cause TIC in childhood are focal atrial tachycardia (FAT) and permanent junctional re-entry tachycardia (PJRT), followed by ventricular tachycardia. In most cases the underlying arrhythmia can be diagnosed in surface electrocardiography (ECG), whereby the morphology of the P&#xa0;waves can provide important indications; however, in some cases the exact localization of the arrhythmogenic substrate is only possible during an electrophysiological examination. The treatment of TCM consists of heart failure treatment and rhythm control. Catheter ablation is a&#xa0;promising treatment even in early childhood if rhythm or frequency control is inadequate under drug treatment, especially if a TCM develops. Once the arrhythmia has been corrected, in most cases the TCM is reversible even with initially high-grade impairment of left ventricular function and clinically severe heart failure.</p>

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Die vielen Gesichter der tachykardieinduzierten Kardiomyopathie (Tachykardiomyopathie)

  • 期刊论文

  • 发表日期：

    2025年4月15日

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  • Viktor Mozes,
  • Heidi Estner,
  • Nikolaus A. Haas,
  • Robert Dalla Pozza,
  • André Jakob,
  • Marcus Fischer

摘要

Dilated cardiomyopathy is the leading reason for heart transplantation in children. Tachycardia-induced cardiomyopathy (TIC), or tachycardiomyopathy (TCM), is a reversible subgroup of cardiomyopathy; therefore, it is important to differentiate this form from other etiologies. Both the electrophysiological substrate of TCM and the clinical picture can be very diverse as shown based on four case examples. The most frequent arrhythmias that can cause TIC in childhood are focal atrial tachycardia (FAT) and permanent junctional re-entry tachycardia (PJRT), followed by ventricular tachycardia. In most cases the underlying arrhythmia can be diagnosed in surface electrocardiography (ECG), whereby the morphology of the P waves can provide important indications; however, in some cases the exact localization of the arrhythmogenic substrate is only possible during an electrophysiological examination. The treatment of TCM consists of heart failure treatment and rhythm control. Catheter ablation is a promising treatment even in early childhood if rhythm or frequency control is inadequate under drug treatment, especially if a TCM develops. Once the arrhythmia has been corrected, in most cases the TCM is reversible even with initially high-grade impairment of left ventricular function and clinically severe heart failure.