<p>As in many areas of medicine, increasing digitalisation is also having an impact on everyday practice in internal medicine, entailing both enormous potential and major challenges. As an interdisciplinary field, usually in cooperation with pneumology, diabetology/endocrinology and haematology/oncology, important questions arise regarding optimal use of digital technologies. These can be of great value, but only if they are geared towards clearly defined medical applications and objectives and create tangible added value. It is therefore important to integrate them sensibly into existing care structures. Digital concepts must meet the specific requirements of different clinical pictures, care settings and all parties involved. Primary goal is the improvement of diagnostics and therapy, efficient use of resources as well as involving patients more closely in treatment processes.</p>