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Background <p>Electrocochleography (ECochG) records electrical potentials of the inner ear and is used, among other applications, in the diagnostic work-up of Ménière’s disease. For extratympanic recordings, age-dependent reference values are currently lacking, which limits clinical interpretation.</p> Objective <p>This study aims to establish age-stratified reference ranges for the summating potential (SP)/action potential (AP) amplitude and area ratios for noninvasive diagnostics in patients with suspected endolymphatic hydrops.</p> Materials and methods <p>A&#xa0;total of 47&#xa0;ears from 26&#xa0;normal-hearing volunteers aged 20–70&#xa0;years were examined using an extratympanic tympanic membrane electrode. The SP and AP potentials were recorded in a&#xa0;standardized manner. Amplitude and area ratios were calculated and analyzed with respect to age and laterality.</p> Results <p>The reference ranges (P5–P95) were 0.13–0.46 for the SP/AP amplitude ratio and 0.72–1.72 for the SP/AP area ratio. No significant side differences were observed. A&#xa0;slight age-related increase in both parameters was detected, without a&#xa0;clinically relevant impact.</p> Conclusion <p>Extratympanic ECochG enables a&#xa0;minimally invasive and reliable diagnostic approach with age-stratified reference values. It represents a&#xa0;practical adjunct to imaging in Ménière’s disease and allows a&#xa0;more differentiated assessment of pathological inner ear function.</p>

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Elektrocochleographie mit Trommelfellelektrode

  • 期刊论文

  • 发表日期：

    2026年2月5日

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  • Tom Gawliczek,
  • Miranda Claire Morrison,
  • Katharine Keller,
  • Athanasia Korda,
  • Stefan Weder,
  • Marco D. Caversaccio,
  • Georgios Mantokoudis

摘要

Background

Electrocochleography (ECochG) records electrical potentials of the inner ear and is used, among other applications, in the diagnostic work-up of Ménière’s disease. For extratympanic recordings, age-dependent reference values are currently lacking, which limits clinical interpretation.

Objective

This study aims to establish age-stratified reference ranges for the summating potential (SP)/action potential (AP) amplitude and area ratios for noninvasive diagnostics in patients with suspected endolymphatic hydrops.

Materials and methods

A total of 47 ears from 26 normal-hearing volunteers aged 20–70 years were examined using an extratympanic tympanic membrane electrode. The SP and AP potentials were recorded in a standardized manner. Amplitude and area ratios were calculated and analyzed with respect to age and laterality.

Results

The reference ranges (P5–P95) were 0.13–0.46 for the SP/AP amplitude ratio and 0.72–1.72 for the SP/AP area ratio. No significant side differences were observed. A slight age-related increase in both parameters was detected, without a clinically relevant impact.

Conclusion

Extratympanic ECochG enables a minimally invasive and reliable diagnostic approach with age-stratified reference values. It represents a practical adjunct to imaging in Ménière’s disease and allows a more differentiated assessment of pathological inner ear function.