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<p>Complications of tattooing occur in 2% of cases and include foreign body granulomas, for which treatment options are limited and often ineffective. Allopurinol, a&#xa0;xanthine oxidase inhibitor, is used to treat granulomatous reactions, but often leads to systemic side effects. Two recent case reports have described topical application as better tolerated. Herein, we report a&#xa0;patient who developed a&#xa0;granulomatous reaction to permanent eyebrow make-up, for which topical allopurinol achieved a&#xa0;satisfactory result.</p>

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Topische Anwendung von Allopurinol bei Tattoo-Granulomen

  • 期刊论文

  • 发表日期：

    2025年8月21日

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  • Caren Meyer zu Altenschildesche,
  • Susanne Triebswetter,
  • Jan Christoph Simon,
  • Anna-Theresa Seitz

摘要

Complications of tattooing occur in 2% of cases and include foreign body granulomas, for which treatment options are limited and often ineffective. Allopurinol, a xanthine oxidase inhibitor, is used to treat granulomatous reactions, but often leads to systemic side effects. Two recent case reports have described topical application as better tolerated. Herein, we report a patient who developed a granulomatous reaction to permanent eyebrow make-up, for which topical allopurinol achieved a satisfactory result.