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<p>Anaplastic thyroid cancer (ATC) is the rarest but also the most aggressive carcinoma entity of the thyroid gland. In recent years, treatment options have evolved and molecular oncological treatment approaches have gained in importance. The neoadjuvant use of these innovative therapies has the potential to convert previously unresectable tumors into a&#xa0;resectable state, thereby expanding surgical options and significantly improving the prognosis of patients. This article provides recommendations relevant for surgery for the diagnostics and treatment of ATC, based on a&#xa0;current literature review and the discussions of the S3&#xa0;guideline conferences.</p>

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Update anaplastisches Schilddrüsenkarzinom – Was ist für Chirurg*innen relevant?

  • 期刊论文

  • 发表日期：

    2025年3月25日

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  • Sabine Wächter,
  • Detlef K. Bartsch

摘要

Anaplastic thyroid cancer (ATC) is the rarest but also the most aggressive carcinoma entity of the thyroid gland. In recent years, treatment options have evolved and molecular oncological treatment approaches have gained in importance. The neoadjuvant use of these innovative therapies has the potential to convert previously unresectable tumors into a resectable state, thereby expanding surgical options and significantly improving the prognosis of patients. This article provides recommendations relevant for surgery for the diagnostics and treatment of ATC, based on a current literature review and the discussions of the S3 guideline conferences.