<p>In the second of two articles the practical application of nontechnical skills in anesthesiological patient care is presented. Based on the categories of the behavioral marker system anesthesia nontechnical skills (ANTS), the skills situational awareness, decision making, task management, teamwork and communication are discussed. For each category the terminology is clarified and the reasons for support through nontechnical skills and their specific application are given. Tips for everyday life should make practical implementation easier. Finally, the health economic question of the extent to which there is a&#xa0;return on investment for the training of nontechnical skills is discussed and the perspective of safety research on the demands of evidence-based medicine (EBM) for analytical empiricism and measurability of the effects of training of nontechnical skills on patient safety is presented.</p>