Scholarlink

Background <p>Advances in oncology and demographic changes are leading to a&#xa0;growing number of critically ill patients with malignancies. In addition to classical indications for intensive care, cardiovascular complications increasingly occur as therapy- or tumor-associated organ manifestations.</p> Objective <p>To describe typical clinical presentations and a&#xa0;pragmatic diagnostic and therapeutic approach, exemplified by acute cardiac dysfunction, arrhythmias, and immune checkpoint inhibitor (ICI)—associated myocarditis.</p> Methods <p>Narrative synthesis of current guidelines, consensus statements, and selected studies with a&#xa0;focus on applicability in the intensive care setting.</p> Results <p>Common complications include acute cardiac dysfunction, thromboembolic events, and arrhythmias. ICI-associated myocarditis is less frequent but highly lethal and requires early recognition and treatment. Early identification based on typical clinical warning signs, structured diagnostics (biomarkers, ECG, echocardiography), consistent trigger control (e.g., sepsis, anemia, electrolyte disturbances, drug interactions), and risk-adapted, guideline-based interdisciplinary management are crucial for patient outcomes.</p> Conclusion <p>Cardio-oncological critical care benefits from standardized pathways, close monitoring, and early goal setting to reduce complications and enable the safe continuation of curative or life-prolonging cancer therapies whenever possible.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Kardioonkologie in der Intensivmedizin

  • 期刊论文

  • 发表日期：

    2026年5月20日

查看全文
  • C. P. E. Rau,
  • H. Lemm,
  • E. Mack,
  • M. Buerke

摘要

Background

Advances in oncology and demographic changes are leading to a growing number of critically ill patients with malignancies. In addition to classical indications for intensive care, cardiovascular complications increasingly occur as therapy- or tumor-associated organ manifestations.

Objective

To describe typical clinical presentations and a pragmatic diagnostic and therapeutic approach, exemplified by acute cardiac dysfunction, arrhythmias, and immune checkpoint inhibitor (ICI)—associated myocarditis.

Methods

Narrative synthesis of current guidelines, consensus statements, and selected studies with a focus on applicability in the intensive care setting.

Results

Common complications include acute cardiac dysfunction, thromboembolic events, and arrhythmias. ICI-associated myocarditis is less frequent but highly lethal and requires early recognition and treatment. Early identification based on typical clinical warning signs, structured diagnostics (biomarkers, ECG, echocardiography), consistent trigger control (e.g., sepsis, anemia, electrolyte disturbances, drug interactions), and risk-adapted, guideline-based interdisciplinary management are crucial for patient outcomes.

Conclusion

Cardio-oncological critical care benefits from standardized pathways, close monitoring, and early goal setting to reduce complications and enable the safe continuation of curative or life-prolonging cancer therapies whenever possible.