Let \(\Sigma \) be a free boundary biharmonic hypersurface in the Euclidean unit ball \(\mathbb {B}^{m+1}\) . Denote by H the mean curvature function on \(\Sigma \) . We prove that \(\Sigma \) satisfies a sharp linear isoperimetric inequality \(m\textrm{Vol}(\Sigma ) \le \textrm{Vol}(\partial \Sigma )\) , where equality holds if and only if \(\Sigma \) is a free boundary minimal hypersurface. Moreover, we prove that \(\Sigma \) is minimal if either H is constant along the boundary or \(H\frac{\partial H}{\partial \nu }\) is nonpositive along the boundary, where \(\nu \) denotes the outward unit conormal vector. These results can be thought of as a partial affirmative answer to Chen’s conjecture.