We study the collinear factorization of off-shell scattering amplitudes in maximally supersymmetric Yang-Mills (sYM) theory. These are constructed starting from six-dimensional \( \mathcal{N} \) = (1) sYM, taking advantage of an available unconstrained spinor-helicity formalism combined with a unitarity-cut sewing procedure. After generalized dimensional reduction, their collinear behavior is dissected with assistance from the Method of Regions. We then construct off-shell splitting amplitudes directly using the same techniques, establishing equivalence to the amplitude analysis. The calculations are performed at one-loop order.