<p>Anomaly detection is a vital technique for exploring signatures of new physics Beyond the Standard Model (BSM) at the Large Hadron Collider (LHC). The vast number of collisions generated by the LHC demands sophisticated deep learning techniques. Similarity learning, a self-supervised machine learning, detects anomalous signals by estimating their similarity to background events. In this paper, we explore the potential of quantum computers for anomaly detection through similarity learning, leveraging the power of quantum computing to enhance the known similarity learning method. In the realm of noisy intermediate-scale quantum (NISQ) devices, we employ a hybrid classical-quantum network to search for heavy scalar resonances in the di-Higgs production channel. In the absence of quantum noise, the hybrid network demonstrates improvement over the known similarity learning method. Moreover, we employ a clustering algorithm to reduce measurement noise from limited shot counts, resulting in 9% improvement in the hybrid network performance. Our analysis highlights the applicability of quantum algorithms for LHC data analysis, where improvements are anticipated with the advent of fault-tolerant quantum computers.</p>