<p>Axions can naturally be very light due to the protection of an (approximate) shift symmetry. Because of their pseudoscalar nature, the long-range force mediated by the axion at tree level is spin dependent, which cannot lead to observable effects between two unpolarized macroscopic objects. At the one-loop level, however, the exchange of two axions does mediate a spin-independent force. This force is coherently enhanced in the presence of an axion background. In this work, we study the two-axion exchange force in a generic axion background. We find that the breaking of the axion shift symmetry plays a crucial role in determining this force. The background-induced axion force <i>V</i>_bkg vanishes in the shift-symmetry restoration limit. The shift symmetry can be broken either explicitly by non-perturbative effects or effectively by the axion background. When the shift symmetry is broken, <i>V</i>_bkg scales as 1<i>/r</i> and could be further enhanced by a large occupation number of the background axions. We investigate possible experimental probes of this effect in two distinct scenarios: an axion dark matter background and a solar axion flux, using fifth-force searches and atomic spectroscopy experiments. In the axion dark matter case, we find that the background-induced axion force can place strong constraints on axion couplings and masses, comparable to existing astrophysical bounds.</p>